WCPO: After 35 years of surviving HIV and AIDS, Carl Fox is part of a study he believes will find a cure
Fox is part of UC's Trailblazer study
Carl Fox of Northern Kentucky found out he was HIV positive in 1985. After decades of living with the virus and watching the deaths of hundreds of friends, he joined a federally funded study and is allowing WCPO-TV to tell his story.
Carl Fichtenbaum, MD, of the UC Division of Infectious Diseases. Photo/Colleen Kelley/UC Creative + Brand
The TRAILBLAZER study, as it’s called, aims to change the parts of a patient’s white blood cells that HIV latches onto, says Carl Fichtenbaum, MD, professor in the Division of Infectious Diseases at the UC College of Medicine.
Fichtenbaum is a principal investigator on the study and has been Fox’s doctor for years.
“The idea behind this study that we’re doing is to take a person’s cells from their white blood cells that harbor that receptor, take it in the laboratory, remove the receptor through genetic engineering and then infuse those cells back into the person,” he tells WCPO.
“Our hope in the future is that perhaps if we were to do this often enough, and change enough cells in the body, that people who have HIV may be able to control the HIV, even without any medication,” Fichtenbaum says. “And it may be the first steps or ideas to really trying to cure people.”
See the full WCPO study here and read more about the TRAILBLAZER study here.
Next Lives Here
The University of Cincinnati is classified as a Research 1 institution by the Carnegie Commission and is ranked in the National Science Foundation's Top-35 public research universities. UC's medical, graduate and undergraduate students and faculty investigate problems and innovate solutions with real-world impact. Next Lives Here.
Related Stories
‘Designer drug’ shows early neuroprotective signal in acute ischemic stroke
October 28, 2025
Medscape highlighted new trial results led by the University of Cincinnati's Eva Mistry that found an experimental drug shows promise in protecting injured brain cells for patients with acute ischemic stroke.
Is menstrual fluid ‘the most overlooked opportunity’ in women’s health?
October 27, 2025
The Guardian recently reported that period blood has long been thought of as ‘stinky and useless’, but startups are exploring using the fluid to test for a wide range of health conditions — including endometriosis.
What is squalane, and how does it work to moisturize skin?
October 27, 2025
The University of Cincinnati's Kelly Dobos was featured in a Women's Health article discussing squalane, an ingredient being increasingly used in moisturizing skincare products.